ID:
SCV0815
Durata (ore):
48
CFU:
6
Anno:
2026
Dati Generali
Periodo di attività
Secondo Semestre (24/02/2027 - 20/06/2027)
Syllabus
Obiettivi Formativi
The course aims to provide students with an understanding of the biological and molecular basis of stem cells and their derivatives, and to explore their role in the study and treatment of human diseases. Emphasis will be placed on the development and application of advanced cell-based technologies in regenerative medicine, including biocompatible three-dimensional (3D) scaffolds combined with stem cells and their derivatives.
The course will also introduce the principles of Good Laboratory Practice (GLP) for working in clean-room environments, as well as the ethical aspects related to the use of stem cells in biomedical research and clinical applications.
In addition to subject-specific knowledge, the course is designed to foster the development of transferable skills by encouraging students to:
1. Take responsibility for their own learning and develop independent study skills.
2. Integrate lecture material through the critical use of scientific literature and other academic resources.
3. Work effectively in multidisciplinary teams, particularly during laboratory activities.
4. Strengthen their communication skills through scientific discussions and oral presentations.
The course will also introduce the principles of Good Laboratory Practice (GLP) for working in clean-room environments, as well as the ethical aspects related to the use of stem cells in biomedical research and clinical applications.
In addition to subject-specific knowledge, the course is designed to foster the development of transferable skills by encouraging students to:
1. Take responsibility for their own learning and develop independent study skills.
2. Integrate lecture material through the critical use of scientific literature and other academic resources.
3. Work effectively in multidisciplinary teams, particularly during laboratory activities.
4. Strengthen their communication skills through scientific discussions and oral presentations.
Prerequisiti
Students are expected to have a basic background in cell biology, molecular biology, biochemistry, and human physiology.
Metodi didattici
The course combines lectures with hands-on laboratory activities. Lectures provide the theoretical background, while laboratory sessions allow students to apply the acquired knowledge through practical experience. The laboratory component is designed to promote independent learning, teamwork, critical thinking, and compliance with laboratory safety and Good Laboratory Practice (GLP) guidelines.
Verifica Apprendimento
The final assessment consists of:
• an individual seminar-style oral presentation based on one of the course topics (PowerPoint presentation recommended);
• a discussion of the laboratory report.
Students are expected to demonstrate a comprehensive understanding of the scientific concepts presented throughout the course and the ability to critically discuss current biomedical applications.
The oral presentation will be evaluated according to the following criteria:
• quality and effectiveness of the slides;
• scientific accuracy, content organization and clarity of the presentation;
• ability to answer questions and engage in scientific discussion;
• compliance with the allotted presentation time.
The oral presentation contributes up to 28/30 of the final grade.
The laboratory report contributes up to 3/30 of the final grade and will be assessed for scientific accuracy, clarity, and critical interpretation of the experimental results.
• an individual seminar-style oral presentation based on one of the course topics (PowerPoint presentation recommended);
• a discussion of the laboratory report.
Students are expected to demonstrate a comprehensive understanding of the scientific concepts presented throughout the course and the ability to critically discuss current biomedical applications.
The oral presentation will be evaluated according to the following criteria:
• quality and effectiveness of the slides;
• scientific accuracy, content organization and clarity of the presentation;
• ability to answer questions and engage in scientific discussion;
• compliance with the allotted presentation time.
The oral presentation contributes up to 28/30 of the final grade.
The laboratory report contributes up to 3/30 of the final grade and will be assessed for scientific accuracy, clarity, and critical interpretation of the experimental results.
Contenuti
1. Lectures (36 hours)
Introduction to stem cells: classification and biological properties
Biology of embryonic and adult stem cells
Cell models for in vitro and in vivo disease studies
Stem cells and their derivatives in regenerative medicine
Cell-based drug delivery systems
Ethical aspects of stem cell research and applications
Principles of Good Laboratory Practice (GLP) and clean-room procedures
Overview of major 3D bioprinting and additive manufacturing technologies
Natural and synthetic biocompatible and bioresorbable materials for tissue engineering
Fundamentals of Computer-Aided Design (CAD) for 3D scaffold modelling and fabrication
2. Laboratory Activities (18 hours)
The laboratory sessions will provide hands-on experience with fundamental techniques used in regenerative medicine and tissue engineering, including:
Isolation of mesenchymal stem cells from adipose tissue
Immunostaining for the assessment of stem cell markers
Cell viability assays on cells cultured within 3D scaffolds
At the end of the laboratory activities, students will prepare a short laboratory report (2–3 pages) summarizing the experimental procedures, results, and conclusions.
The laboratory component is designed to promote independent learning, teamwork, critical thinking, and compliance with laboratory safety procedures.
Introduction to stem cells: classification and biological properties
Biology of embryonic and adult stem cells
Cell models for in vitro and in vivo disease studies
Stem cells and their derivatives in regenerative medicine
Cell-based drug delivery systems
Ethical aspects of stem cell research and applications
Principles of Good Laboratory Practice (GLP) and clean-room procedures
Overview of major 3D bioprinting and additive manufacturing technologies
Natural and synthetic biocompatible and bioresorbable materials for tissue engineering
Fundamentals of Computer-Aided Design (CAD) for 3D scaffold modelling and fabrication
2. Laboratory Activities (18 hours)
The laboratory sessions will provide hands-on experience with fundamental techniques used in regenerative medicine and tissue engineering, including:
Isolation of mesenchymal stem cells from adipose tissue
Immunostaining for the assessment of stem cell markers
Cell viability assays on cells cultured within 3D scaffolds
At the end of the laboratory activities, students will prepare a short laboratory report (2–3 pages) summarizing the experimental procedures, results, and conclusions.
The laboratory component is designed to promote independent learning, teamwork, critical thinking, and compliance with laboratory safety procedures.
Lingua Insegnamento
INGLESE
Altre informazioni
Given the multidisciplinary nature of the course, there is no single recommended textbook. Teaching material will consist of lecture slides together with selected review papers and original research articles provided by the instructors through-out the course.
The teachers receive the students by appointment via e-mail (rosalba.gornati@uninsubria.it; ludovica.barone@uninsubria.it).
The teachers receive the students by appointment via e-mail (rosalba.gornati@uninsubria.it; ludovica.barone@uninsubria.it).
Corsi
Corsi
BIOTECHNOLOGY FOR THE BIO-BASED AND HEALTH INDUSTRY
Laurea Magistrale
2 anni
No Results Found
Persone
Persone (2)
Assegnisti
Docenti di ruolo di Ia fascia
No Results Found