Magnetic hyperthermia efficiency of Mn doped Fe oxides particles loaded into PLGA

The chemical, geometric and thermal properties of nanofluid obtained dispersing the same type of nanoparticles in water, octane and buffer solution after inclusion in polylactic and glycolic acid (PLGA) were investigated by means of an experimental set-up in adiabatic conditions. The Mn-ferrite nanoparticle were obtained by thermal decomposition. The aim is to obtain some very thermally performant nanoparticles suitable to treat cancer by Magnetic Fluid Hyperthermia (MFH). The heating properties of 1 ml suspension samples of the NPs were studied applying a time varying magnetic field of 27.1 kA/m at 245 kHz, a typical frequency for MFH, using a power generator and a cylindrical inductor.