Accuracy of multislice CT in restaging patients with non-small cell lung carcinoma after neoadjuvant chemotherapy using a multiparametric approach.

The aim of this study was to assess diagnostic
accuracy of multislice CT in restaging patients with N2 nonsmall
cell lung carcinoma after neoadjuvant chemotherapy,
using a multiparametric approach as compared with traditional
size-based radiological criteria.
All patients staged as N2 at histologic examination after
neoadjuvant chemotherapy were correctly staged with multislice
CT (sensitivity, specificity, positive and negative predictive
value, and accuracy were 100%, 80%, 85%, 100% and
93,7% respectively, vs 34%, 60%, 34%, 60% and 50% using
size-based criteria), suggesting that a multiparametric approach
results in improved diagnostic accuracy.