Synthesis of 1,4-benzodiazepinones via palladium-catalysed allene carbopalladation/amination domino sequence

Vinyl-substituted 1,4-benzodiazepinones were obtained in good yields (10 examples, 61-82% yield) via the reaction between N-allenyl anthranyl amides and aryl iodides under Pd(0) catalysis. This new single cycle catalytic domino transformation involves a C-C followed by an N-C bond formation.