Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase.

Salvi, E; Kutalik, Z; Glorioso, N; Benaglio, P; Frau, F; Kuznetsova, T; Arima, H; Hoggart, C; Tichet, J; Nikitin, Yp; Conti, C; Seidlerova, J; Tikhonoff, V; Stolarz Skrzypek, K; Johnson, T; Devos, N; Zagato, L; Guarrera, S; Zaninello, R; Calabria, A; Stancanelli, B; Troffa, C; Thijs, L; Rizzi, F; Simonova, G; Lupoli, S; Argiolas, G; Braga, D; D'Alessio, Mc; Ortu, Mf; Ricceri, F; Mercurio, M; Descombes, P; Marconi, M; Chalmers, J; Harrap, S; Filipovsky, J; Bochud, M; Iacoviello, Licia; Ellis, J; Stanton, Av; Laan, M; Padmanabhan, S; Dominiczak, Af; Samani, Nj; Melander, O; Jeunemaitre, X; Manunta, P; Shabo, A; Vineis, P; Cappuccio, Fp; Caulfield, Mj; Matullo, G; Rivolta, C; Munroe, Pb; Barlassina, C; Staessen, Ja; Beckmann, Js; Cusi, D.