Data di Pubblicazione:
2015
Abstract:
Purpose
– Magnetic fluid hyperthermia experiment requires a uniform magnetic field in order to control the heating rate of a magnetic nanoparticle fluid for laboratory tests. The automated optimal design of a real-life device able to generate a uniform magnetic field suitable to heat cells in a Petri dish is presented. The paper aims to discuss these issues.
Design/methodology/approach
– The inductor for tests has been designed using finite element analysis and evolutionary computing coupled to design of experiments technique in order to take into account sensitivity of solutions.
Findings
– The geometry of the inductor has been designed and a laboratory prototype has been built. Results of preliminary tests, using a previously synthesized and characterized magneto fluid, are presented.
Originality/value
– Design of experiment approach combined with evolutionary computing has been used to compute the solution sensitivity and approximate a 3D Pareto front. The designed inductor has been tested in an experimental set-up.
– Magnetic fluid hyperthermia experiment requires a uniform magnetic field in order to control the heating rate of a magnetic nanoparticle fluid for laboratory tests. The automated optimal design of a real-life device able to generate a uniform magnetic field suitable to heat cells in a Petri dish is presented. The paper aims to discuss these issues.
Design/methodology/approach
– The inductor for tests has been designed using finite element analysis and evolutionary computing coupled to design of experiments technique in order to take into account sensitivity of solutions.
Findings
– The geometry of the inductor has been designed and a laboratory prototype has been built. Results of preliminary tests, using a previously synthesized and characterized magneto fluid, are presented.
Originality/value
– Design of experiment approach combined with evolutionary computing has been used to compute the solution sensitivity and approximate a 3D Pareto front. The designed inductor has been tested in an experimental set-up.
Tipologia CRIS:
Articolo su Rivista
Keywords:
Finite element analysis; Magnetic fluid hyperthermia; Magnetic nanoparticles; Multi-objective optimization; Sensitivity analysis; Uniform magnetic field; Computational Theory and Mathematics; Computer Science Applications1707 Computer Vision and Pattern Recognition; Software; Engineering (all)
Elenco autori:
Bertani, Roberta; Ceretta, Flavio; Di Barba, Paolo; Dughiero, Fabrizio; Forzan, Michele; Michelin Rino, Antonio; Sgarbossa, Paolo; Sieni, Elisabetta; Spizzo, Federico
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