Self-adaptive NGSA algorithm and optimal design of inductors for magneto-fluid hyperthermia

Purpose – This paper aims to present the optimal design of an inductor used to heat a magnetic nanoparticle
fluid injected in a cell culture inside a Petri dish.
Design/methodology/approach – The inductor design is driven by means of a multi-objective
optimization algorithm that generalizes the migration-non-dominated sorting genetic algorithm (NSGA); it is
called self-adapting migration-NSGA.
Findings – The optimized device is able to synthesize a uniform magnetic field in a nanoparticle fluid,
substantially helping its heating capability. The ultimate scope is to assist the cancer therapy based on
magnetic fluid hyperthermia (MFH).
Originality/value – The optimal design of an inductor for MFH applications has been carried out by
applying an improved version of migration-based NSGA-II algorithm including automatic stop and a
self-adapting concept. The modified optimization algorithm is suitable to find better optimal solutions with
respect to a standard version of NSGA-II.