The Physiology course aims to introduce the students to a biophysical and quantitative analysis of the functionality of cells, tissues and organs of the human body. The course provides students with the tools to understand the complexity of physiological functions The objectives of the Course of Human Physiology are 1.To describe functional parameters characterizing the physiological behavior of cells, tissues and organs; 2.To explain how cells and tissues function; 3.To appropriately use biophysical-quantitative tools (such as equations and graphs) to describe physiological mechanisms; 4.To describe morpho-functional and biophysical correlations of organs and systems of the human body; 5.To describe mechanisms underlying the coordinated and interactive cooperation between organs and systems; 6.To analyze the mechanisms leading to alterations of body homeostasis; 7.To properly discuss topics of Physiology, using an appropriate terminology; 8.To explain how perturbances in body homeostasis affect cells, tissues, and organs behavior, leading to physio-pathological conditions.
Course Prerequisites
To be admitted to the final exam of Human Physiology it is necessary to possess a positive evaluation of the exam of Morphological Foundations of life
Teaching Methods
The teaching will be given through lectures, with slides. The student will be guided to the understanding of different, but integrated, physiological processes, with the aid of images, diagrams, graphs, and biophysical analysis of mechanisms involving cells, tissues, and organs. Slides will be available on the e-learning page of the Human Physiology course.
Assessment Methods
The final evaluation consists in a multiple-choice, PC-based exam, organized in 40 questions on the entire Human Physiology course program. Each question earns 0.825 for a correct answer, and 0 for each wrong or missing answer. The exam aims at defining the understanding and the degree of comprehensions of the human physiological mechanisms, the capacity to apply knowledge and comprehension and the learning capacity of the issues dealt within the Course. The exam is passed for final scores equal to or higher than 18/33.
Contents
Topics of the course: - Body compartments - Biophysics of blood and body fluids - Cell electrophysiology: membrane resting potential, action potential; synapses - Functional specialization of cortical areas - Sensory Physiology: general overview, somatosensory systems (touch, proprioception, thermal sensitivity, pain), vision, hearing, vestibular system, smell and taste - Skeletal muscle: neuromotor unit, motor unit, muscle contraction; twitch, clonus and tetanus.; length-tension and tension-velocity plots - Motor control - Hypothalamus; Autonomic Nervous System - Heart and circulatory system: blood, hemostasis and coagulation. Electrocardiogram, cardiac contraction, hemodynamics, Poiseuille’s Law, Bernoulli’s Law. Capillary fluid exchange, lymphatic system, pulmonary circulation, cardiac output - Respiratory system: lung volumes, , lung and chest-wall relaxation pressure-volume plots, pulmonary surfactant, respiratory cycle, pulmonary and alveolar ventilatory flow, O2 consumption and CO2 production, alveolar gas equation, alveolus-capillary gas exchange, transport of O2 and CO2 in the blood - Urinary system: glomerular filtration, Clearence, proximal tubule, Henle’s loop, distal convoluted tubule and collecting duct - Acid-base regulation, physiological buffer systems, acidosis and alkalosis, blood pH regulation by respiratory and renal systems. - Energetic metabolism and thermal regulation - Gastrointestinal physiology: gastrointestinal motility and secretions, control of gastric function. Nutrients’ digestion and absorption, glucose homeostasis - Endocrine system and gland of human body
Course Language
Italian
More information
Dr. Solari receives by appointment. Please contact the teacher by email at eleonora.solari@uninsubria.it