The course, which is adressed to students of all chemical fields, proposes, through the discussion of different topics, specific to organic chemistry and strongly interdisciplinary, to make students understand: a) The great importance of the shape of the molecules and of the spatial arrangement of the atoms on their physical and biological properties (static organic stereochemistry) b) Engineering challenges in the construction of molecules with special dynamic properties related to the presence of mechanical and non-chemical bonds (molecular machines and topological stereoisomers) c) The rules imposed by the electronic structure of reactive molecules in some transformations, such as pericyclic reactions, of great theoretical and applicative relevance (cycloadditions, electrocyclic reactions, sigmatropic transpositions) The student is expected to learn new tools that allow him to surprisingly predict certain properties, reactivity and obedience to external stimuli of simple and complex organic molecules
Course Prerequisites
The prerequisites are the course contents of Organic Chemistry 1 and 2.
Teaching Methods
The course includes 48 hours of lectures consisting in theoretical lessons and application exercises. The lessons will be conducted with the support of slides.
Assessment Methods
The exam consists of a 2-3 hour written test with open questions on the three main topics covered and application-type exercises related to static stereochemistry and pericyclic reactions.
Contents
The course is divided into 3 modules: a) Stereochemistry (18 hours). b) Topological Stereoisomers and Molecular Machine (10 hours). c) Pericyclic reactions (20 hours).
