Publication Date:
2012
abstract:
The global distribution of the new cases of type 1 diabetes is influenced
by genetic and environmental factors. The genetic component is not restricted to
HLA, as other loci participate as risk factors. The incidence of type 1 diabetes in
tropical/subtropical regions is low, whereas helminth and enterovirus infections are
common and widespread. Three Echovirus epidemics have been documented in
Cuba over the last two decades. Echovirus infections were associated with seroconversion
to diabetes-related autoantibodies. Data from Cuba indicate enteroviruses
of the B species as the agents linked most frequently to type 1 diabetes. Further
research is necessary to define the enterovirus types linked to type 1 diabetes, which
will pave the way for designing novel preventive approaches.
by genetic and environmental factors. The genetic component is not restricted to
HLA, as other loci participate as risk factors. The incidence of type 1 diabetes in
tropical/subtropical regions is low, whereas helminth and enterovirus infections are
common and widespread. Three Echovirus epidemics have been documented in
Cuba over the last two decades. Echovirus infections were associated with seroconversion
to diabetes-related autoantibodies. Data from Cuba indicate enteroviruses
of the B species as the agents linked most frequently to type 1 diabetes. Further
research is necessary to define the enterovirus types linked to type 1 diabetes, which
will pave the way for designing novel preventive approaches.
Iris type:
Capitolo di Libro
Keywords:
Diabetes; autoimmunity; epidemiology; etiology
List of contributors:
E., Cabrera Rode; O., Díaz Horta; Toniolo, Antonio; L., Sarmiento
Book title:
Diabetes and Viruses