Person
TRINCHERA MARCO GIUSEPPE
Docenti di ruolo di IIa fascia
Course Catalogue:
Communications
Overview
MD PhD (biochemistry), associate professor of biochemistry, expertise in glycobiology with focus on glycosyltransferases and their involvement in tumor marker biosynthesis and congenital disorders of glycosylation
Attachment (CV)
Curric MT 02 26.docx (CV completo attività scientifica e didattica)
Description
- Born in Milan (Italy), June 30, 1961, married and with three children
- Degree in Medicine, July 21, 1987, University of Milan Medical School (Italy)
- Ph.D. in Biochemistry, June 1993, MURST, Rome (Italy),
- Recognition of Postdoctoral Training, September 1993, University of Michigan, Ann Arbor, Michigan (USA)
Appointments
- 1983/1988 - Graduate student at the Department of Medical Chemistry and Biochemistry, University of Milan (Italy)
- 1988 - Postdoctoral fellow at the Department of Chemistry (Biochemistry, Biophysics and Molecular Biology Program), Notre Dame University, Notre Dame, IN (USA)
- 1988/1991- Postdoctoral fellowship as partial requirement for Ph.D. graduation in Biochemistry at the Department of Medical Chemistry and Biochemistry, University of Milan (Italy)
- 1991/1993 - Postdoctoral fellow at the Department of Pathology, University of Michigan, Ann Arbor, Michigan (USA)
- 1994/1995 - Postdoctoral fellowship at the Department of Clinical and Biological Sciences, University of Torino, Orbassano (TO) (Italy)
- 1995/1998 - Researcher (tenure-tracked permanent position) at the University of Pavia Medical School II, Department of Biochemistry,
Pavia (Italy)
- 1998/2018 - Researcher (tenured) at the University of Insubria Medical School, Department of Experimental and Clinical Biomedical Sciences, then Dept.of Clinical and Experimental Medicine, then Dept. of Medicine and Surgery
- 2018 - Associate professor of Biochemistry at the University of Insubria Medical School, Department of Medicine and Surgery
- Publications: 63 papers and 30 meeting proceedings
- Invited speakers at the Gordon Conference on Glycolipids and Sphingolipids, November 15-20, 1992, Hawaii Is.
- Funded projects:
- (1996) AIRC "Molecular cloning of glycosyltransferases which synthesize tumor markers associated with malignancy"
- (1997) Telethon "Molecular cloning of beta 1,3galactosyltransferase cDNA(s) responsible for the biosynthesis of epitopes recognized by motor neuron disease patient sera"
- (2001) COFIN "Molecular mechanisms regulating the expression of CA19.9 and other adhesion molecules in colorectal cancer"
- (2004) PRIN "Down-regulation of a galactosyltransferase gene:molecular analysis and involvement in colorectal cancer malignancy"
- (2008) Mizutani Foundation for Glycoscience (Tokio, Japan) “Transcriptional and epigenetic silencing of b1,3-galactosyltransferase 5 in cancer”;
- (2021) "Novel diseases reveal glycosylations affecting human specific brain functions", finanziato da Mizutani Foundation for Glycoscience (Tokio, Japan)
- Degree in Medicine, July 21, 1987, University of Milan Medical School (Italy)
- Ph.D. in Biochemistry, June 1993, MURST, Rome (Italy),
- Recognition of Postdoctoral Training, September 1993, University of Michigan, Ann Arbor, Michigan (USA)
Appointments
- 1983/1988 - Graduate student at the Department of Medical Chemistry and Biochemistry, University of Milan (Italy)
- 1988 - Postdoctoral fellow at the Department of Chemistry (Biochemistry, Biophysics and Molecular Biology Program), Notre Dame University, Notre Dame, IN (USA)
- 1988/1991- Postdoctoral fellowship as partial requirement for Ph.D. graduation in Biochemistry at the Department of Medical Chemistry and Biochemistry, University of Milan (Italy)
- 1991/1993 - Postdoctoral fellow at the Department of Pathology, University of Michigan, Ann Arbor, Michigan (USA)
- 1994/1995 - Postdoctoral fellowship at the Department of Clinical and Biological Sciences, University of Torino, Orbassano (TO) (Italy)
- 1995/1998 - Researcher (tenure-tracked permanent position) at the University of Pavia Medical School II, Department of Biochemistry,
Pavia (Italy)
- 1998/2018 - Researcher (tenured) at the University of Insubria Medical School, Department of Experimental and Clinical Biomedical Sciences, then Dept.of Clinical and Experimental Medicine, then Dept. of Medicine and Surgery
- 2018 - Associate professor of Biochemistry at the University of Insubria Medical School, Department of Medicine and Surgery
- Publications: 63 papers and 30 meeting proceedings
- Invited speakers at the Gordon Conference on Glycolipids and Sphingolipids, November 15-20, 1992, Hawaii Is.
- Funded projects:
- (1996) AIRC "Molecular cloning of glycosyltransferases which synthesize tumor markers associated with malignancy"
- (1997) Telethon "Molecular cloning of beta 1,3galactosyltransferase cDNA(s) responsible for the biosynthesis of epitopes recognized by motor neuron disease patient sera"
- (2001) COFIN "Molecular mechanisms regulating the expression of CA19.9 and other adhesion molecules in colorectal cancer"
- (2004) PRIN "Down-regulation of a galactosyltransferase gene:molecular analysis and involvement in colorectal cancer malignancy"
- (2008) Mizutani Foundation for Glycoscience (Tokio, Japan) “Transcriptional and epigenetic silencing of b1,3-galactosyltransferase 5 in cancer”;
- (2021) "Novel diseases reveal glycosylations affecting human specific brain functions", finanziato da Mizutani Foundation for Glycoscience (Tokio, Japan)
Concepts (3)
Overview (3)
Congenital disorders of glycosylation affecting glycisphingolipids
Glycosyltransferases in physiology and diseases
Lewis type charbohydrate antigens in gastrointestinal cancer
No Results Found
Member of
Glicobiology
GroupCollaborates with
Glicobiology
GroupPublications (63)
Fellowship
fs2 – Socio/a effettivo o corrispondente
- ASBMB, American Society for Biochemistry and molecular biology (Stati Uniti)
(2001 - 2031)
2001
No Results Found
Editorial Board
Editor di rivista, collana editoriale, enciclopedia - BIOMEDICINES - ISSN: 2227-9059 - Basel: MDPI (2021 - 2031)
2021
No Results Found
Research Network (4)
Novel diseases reveal glycosylations affecting human specific brain functions
- Coordinamento e direzione di un gruppo di ricerca finalizzato al progetto "Novel diseases reveal glycosylations affecting human specific brain functions", che coinvolge l'Università dell'Insubria, di Milano, di Bologna, di Napoli, di Tehran (Iran) ed il TIGEM di Pozzuoli
(01/01/2021 - 31/12/2023)20210101
Malattie congenite della glicosilazion
- Coordinamento e direzione di un gruppo di ricerca riguardante le malattie congenite della glicosilazione che ha coinvolto l'Università dell'Insubria, l'Università di Milano, l'Università di Bologna, l'ASST Papa Giovanni XXIII - Bergamo, e la Fondazione MBBM, Ospedale San Gerardo - Monza
(01/01/2017 - 31/12/2020)20170101
Ruolo di glicosiltransferasi nell’espressione del tetrasaccaride sialil-Lewis a epitope del marcatore tumorale CA19.9
- Coordinamento e direzione di un gruppo di ricerca inerente il ruolo di glicosiltransferasi nell’espressione del tetrasaccaride sialil-Lewis a epitope del marcatore tumorale CA19.9, che ha coinvolto le Università dell'Insubria, di Milano, di Bologna e di Pavia.
(01/01/2012 - 31/12/2014)20120101
Regolazione di glicosiltransferasi coinvolte nella biosintesi di marcatori tumorali
- Coordinamento e direzione di un gruppo di ricerca inerente la regolazione di glicosiltransferasi coinvolte nella biosintesi di marcatori tumorali che ha coinvolto le Università dell'Insubria, di Milano e di Bologna.
(01/01/2010 - 31/12/2012)20100101
No Results Found
Agreement Management
Peer Reviewer (4)
Preproposal-PRO-26-35 Tracking lipid pathway dysfunction to accelerate antisense gene therapy for GBA Parkinson’s disease
- commissioned by:
Parkinson's UK -
2026
2026
NMTFMT Leigh Syndrome french patient organization - B4GALNT1: The Molecexus Linking MTFMT Deficiency to Systemic Lipid Dysregulation
- commissioned by:
Fondation Maladies Rares -
2026
2026
Research Projects Call identifier: IP-2022-10 The role of plasma and mitochondrial membrane gangliosidome in neuronal energy metabolism and mitochondrial dysfunction
- commissioned by:
Croatian Science Foundation (HRZZ) -
2023
2023
Competition Domain Science Package 22-1 Title CRACKING CARBOHYDRATE CUES FOR STEMNESS PROGRAMS IN COLORECTAL CANCER
- commissioned by:
Dutch Research Council (NWO) -
2022
2022
No Results Found
Supervision of external doctoral students or post-docs (3)
Dottorando -
Montavoci Linda
-
Università degli Studi di Milano -
(01/11/2022 - 31/10/2025)
20221101
Dottorando -
Indellicato Rossella
-
Università degli Studi di Milano -
(01/11/2018 - 31/10/2021)
20181101
Dottorando -
Aronica Adele
-
Università degli Studi di Milano -
(01/11/2012 - 31/10/2015)
20121101
Courses (8)
3 CFU
40 hours
2 CFU
24 hours
7 CFU
84 hours
6 CFU
72 hours
2 CFU
30 hours
2 CFU
30 hours
5 CFU
75 hours
5 CFU
75 hours
No Results Found