Emergence of SARS-COV-2 Spike Protein Escape Mutation Q493R after Treatment for COVID-19

Articolo

Data di Pubblicazione:

2021

Abstract:

We report in vivo selection of a severe acute respiratory syndrome coronavirus 2 spike mutation (Q493R) conferring simultaneous resistance to bamlanivimab and etesivimab. This mutation was isolated from a patient who had coronavirus disease and was treated with these drugs.

Tipologia CRIS:

Articolo su Rivista

Keywords:

COVID-19; Italy; SARS-CoV-2; bamlaniv/etesevimab; coronavirus disease; coronaviruses; receptor-binding motif; respiratory infections; severe acute respiratory syndrome coronavirus 2; spike protein; spike protein escape mutation Q493R; treatment; variant; viruses; zoonoses

Elenco autori:

Focosi, Daniele; Novazzi, Federica; Genoni, Angelo; Dentali, Francesco; Gasperina, Daniela Dalla; Baj, Andreina; Maggi, Fabrizio

Autori di Ateneo:

BAJ ANDREINA

DALLA GASPERINA DANIELA

DENTALI FRANCESCO

GENONI ANGELO PAOLO

MAGGI FABRIZIO

NOVAZZI FEDERICA

Link alla scheda completa:

https://irinsubria.uninsubria.it/handle/11383/2114544

Link al Full Text:

https://irinsubria.uninsubria.it//retrieve/handle/11383/2114544/147378/EID-Protein%20Escape%20Mutation%20Q493R%20after%20Treatment%20for%20COVID-19%20-%20Volume%2027,%20Number%2010%BFOctober%202021%20-%20Emerging%20Infectious%20Diseases%20journal%20-%20CDC.pdf

https://irinsubria.uninsubria.it//retrieve/handle/11383/2114544/367039/21-1538.pdf

Pubblicato in:

EMERGING INFECTIOUS DISEASES

Journal