The main objective is to reach an appropriate knowledge of hematological malignancies and diseases. Students will be asked to know and to discuss on pathogenesis of hematological diseases, how to reach a final diagnosis, which is the clinical phenotype of patients and which are the most used and updated prognostic systems to predict events. The student will be able to discern among conditions affecting blood cells, discussing diagnoses and prognostication systems. This will allow to know where oncologic medicine is going
Course Prerequisites
It is of main relevance that students know physiology of hematopoiesis and in general genetics and molecular biology related to oncogenesis.
Teaching Methods
Teaching will be based on frontal lessons, and discussion of e-cases using e-learning system
Contents
Lessons will focus on: 1. Hematopoiesis: Hematopoiesis will be displayed with all physiologic aspects of maturation and proliferation. Morphology of cells will be presented as well as the indication for the procedure of bone marrow biopsy. 2. Anemias Role and function of red cells and of hemoglobin will be presented; clinical and laboratoristic strategies to diagnose anemias, classification and algorithms of anemias, etiology, incidence, pathophysiology, clinic phenotype, diagnosis of anemias will be disclosed. 3. Bleeding disorders Role and function of platelets will be presented; clinical and laboratoristic strategies to diagnose thrombocytopenias, platelet dysfunction, and coagulation disorders (congenital and acquired) will be displayed; classification, etiology, incidence, pathophysiology, clinic phenotype, diagnosis of bleeding disorders will be disclosed. 4. Myeloid neoplasms Role and function of leukocytes will be presented; 2016 WHO classification of myeloid neoplasms will be discussed; clinical and laboratoristic strategies to diagnose myeloid neoplasms will be displayed; etiology, incidence, molecular pathophysiology, clinic phenotype, diagnosis of myeloid neoplasms will be disclosed. 5. Lymphoid neoplasms Role and function of lymphocytes will be presented; 2016 WHO classification of lymphoid neoplasms will be discussed; clinical and lab strategies to diagnose lymphoid neoplasms will be displayed; etiology, incidence, molecular pathophysiology, clinic phenotype, diagnosis of lymphoid neoplasms will be disclosed. 6. Plasma cell disorders Clinical and lab strategies to diagnose monoclonal gammopathy will be presented; diagnosis, etiology, incidence, pathophysiology, clinic phenotype, diagnosis of monoclonal gammopaties will be shown.
Course Language
Italian
More information
Reception hours: by appointment, to be agreed via e-mail, or directly, at the end of each lesson
