Emergence of SARS-COV-2 Spike Protein Escape Mutation Q493R after Treatment for COVID-19

Academic Article
Publication Date:
2021
abstract:
We report in vivo selection of a severe acute respiratory syndrome coronavirus 2 spike mutation (Q493R) conferring simultaneous resistance to bamlanivimab and etesivimab. This mutation was isolated from a patient who had coronavirus disease and was treated with these drugs.
Iris type:
Articolo su Rivista
Keywords:
COVID-19; Italy; SARS-CoV-2; bamlaniv/etesevimab; coronavirus disease; coronaviruses; receptor-binding motif; respiratory infections; severe acute respiratory syndrome coronavirus 2; spike protein; spike protein escape mutation Q493R; treatment; variant; viruses; zoonoses
List of contributors:
Authors of the University:
Handle:
https://irinsubria.uninsubria.it/handle/11383/2114544
Full Text:
Published in:
EMERGING INFECTIOUS DISEASES
Journal