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Uncomplicated Type B Aortic Dissection: A European Multicentre Cross-Sectional Evaluation

Articolo
Data di Pubblicazione:
2024
Abstract:
Background: A multicentre European randomized control trial – European Uncomplicated Type B Aortic Repair (EU-TBAR) is being developed to compare pre-emptive thoracic endovascular aortic repair (TEVAR) with custom-made devices versus conventional optimal medical therapy. The pretrial set-up is confluent on different pillars, including evaluation of 1) European activity, trends, and governance; 2) outcome reporting; and 3) cost evaluation. This article aimed to demonstrate the observational cross-sectional survey results from participating centers and highlight the risk assessment, activity, practices, and governance of uncomplicated type B aortic dissection (uTBAD). Methods: This observational cross-sectional European survey used a questionnaire that examined the understanding, risk assessment, local governance oversight, and clinical activity of uTBAD. The data were collected and managed using Research Electronic Data Capture (REDCap). Results: Out of 43 surveyed surgeons, 37 (86%) responded within a month from 14 European countries. Most reported low annual uTBAD encounters, with autumn being the most common season for cases. Pre-emptive TEVAR was recommended by 43.2% of participants, who favored subacute intervention timing. The Gore TAG was the most used TEVAR device, and custom devices were available for 73% of respondents. Risk factors for uTBAD were ranked, with 'Rapid Aortic Enlargement' deemed most critical. A majority of centers had protocols and multidisciplinary teams, with most having readily available radiology services. Only 45.9% had transfer services to specialized centers. Conclusions: uTBAD remains a misnomer of a dynamic, ongoing disease process requiring early diagnosis and intervention. Pre-emptive TEVAR in high-risk uTBAD is becoming more common, with encouraging results prompting an expansion of indication criteria to a broader uTBAD population managed conservatively. Nevertheless, further evidence is needed through large randomized controlled trials, mainly European collaboratives, to reach a definitive conclusion on the optimum surgical management of uTBAD.
Tipologia CRIS:
Articolo su Rivista
Elenco autori:
Bashir, M.; Jubouri, M.; Surkhi, A. O.; Williams, I. M.; Davidovic, L. B.; Koncar, I.; Baltrunas, T.; Kunt, A.; Tanyeli, O.; Bayram, M.; Ugur, M.; Rossi, G.; Stelzmueller, M. -E.; Hoksbergen, A. W. J.; Jongkind, V.; Bertoglio, L.; Zaca, S.; Mansour, W.; Sirignano, P.; D'Oria, M.; Tolva, V. S.; Van Herzeele, I.; Klincheva, M.; Atanasov, Z.; Bartoli, S.; Bellosta, R.; Chisci, E.; Guagliano, A.; Teraa, M.; Ivak, P.; Recicarova, S.; Pellenc, Q.; Heijmen, R.; Pfister, K.; Piffaretti, G.; Hutchings, H.; Holland, G.; Bailey, D. M.; Thielmann, M.; Jakob, H.
Autori di Ateneo:
Centro di ricerche per lo studio e l'applicazione di nuove tecnologie in chirurgia vascolare
PIFFARETTI GABRIELE
Link alla scheda completa:
https://irinsubria.uninsubria.it/handle/11383/2187432
Pubblicato in:
ANNALS OF VASCULAR SURGERY
Journal
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