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VIGETTI DAVIDE

VIGETTI DAVIDE

Docenti di ruolo di IIa fascia
DIPARTIMENTO DI MEDICINA E CHIRURGIA
Course Catalogue:
https://uninsubria.coursecatalogue.cineca.it/docen...

Gruppo 05/BIOS-07 - BIOCHIMICA

Settore BIOS-07/A - Biochimica
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  •  Davide.Vigetti@uninsubria.it
  •  0332 39 7170
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Communications

Overview

Davide Vigetti is a biochemist and Associate Professor at the University of Insubria.His teaching activities are carried out within the School of Medicine at the University of Insubria, where he holds several teaching positions in Chemistry and Biochemistry for degree programs in Medicine and Surgery, Dentistry, Nursing, Sports Science, and Biomedical Laboratory Techniques. He is a member of the Faculty Board of the PhD program in "Life Sciences and Biotechnology" and serves on the Board of the Specialization School in Clinical Pathology and Clinical Biochemistry.His scientific research focuses on the study of the extracellular matrix, with a specific interest in hyaluronan (hyaluronic acid) metabolism.In summary, his main research lines include:Regulation of hyaluronan synthesis: He studies the molecular mechanisms controlling HAS (Hyaluronan Synthases) enzymes, with a particular focus on post-translational modifications (such as $O$-GlcNAcylation and phosphorylation) and epigenetic regulation.Tumor microenvironment: He investigates the role of hyaluronan in cancer progression, angiogenesis, and the ability of tumor cells to develop drug resistance (chemoresistance).Inflammation and vascular diseases: He analyzes how matrix accumulation influences pathological processes such as atherosclerosis and diabetes-related complications.Non-coding RNAs: A significant part of his recent research concerns the role of microRNAs and long non-coding RNAs (lncRNAs) in the regulation of cellular metabolism.His work contributes to understanding how fundamental chemical alterations at the molecular level can lead to chronic and degenerative diseases.

Attachment (CV)

Vigetti CV 2026 EN.pdf (CV Davide Vigetti 2026 ENGL)

Description

DAVIDE VIGETTI
Nato il 17/01/1972 a Varese

EDUCATION
2002 Ph.D. in Evolutionary and Developmental Biology, University of Milan, Italy.
1996 Degree in Biology, University of Milan, Italy.

ACADEMIC APPOINTMENTS

Associate Professor of Biochemistry, Department of Medicine and Surgery, University of Insubria, Varese, Italy
Assistant Professor of Biochemistry, University of Insubria, Varese (2004-2014)
National Scientific Qualification (ASN) to function as Full Professor in Bio/10 - Biochemistry

SOCIETIES
American Society of Biochemistry and Molecular Biology
Italian Society of Biochemistry and Molecular Biology
Italian Society of Connective Tissue Research (secretary 2017-2022)
International Society of Hyaluronan Sciences (secretary 2018-2021)
International Society for Matrix Biology

AWARDS
2013 FEBS Journal Top-cited paper Award
2008 Young Researcher Award from Centro Insubre di Biotecnologie per la Salute Umana - University of Insubria
2001 Postdoctoral fellowship, University of Insubria

EDITORIAL APPOINTMENTS
Editorial Board of the Journal of Biological Chemistry, BMC Cancer, Biomolecules, and Clinical & Medical Biochemistry

RESEARCH ACTIVITIES
Role of the cellular microenvironment on cell behavior and connective tissue pathology focusing on vascular and tumor biology. Specific interests include molecular aspects of the regulation of extracellular matrix components as hyaluronan and proteoglycans (glycobiology, epigenetics, long non-coding RNA, post-translational modifications such as phosphorylation, acetylation, O-GlcNAcylation).

FINANCIAL SUPPORT
EU H2020, MIZUTANI FOUNDATION, FOCOVA ONLUS, EU FP7, PRIN, FONDAZIONE CARIPLO, CONSORZIO INTERUNIVERSITARIO PER LE BIOTECNOLOGIE

BIBLIOGRAPHY
Davide Vigetti is author of 90 papers with more than 3300 citations, and an H-index is 32.
For a complete list of publications see: https://pubmed.ncbi.nlm.nih.gov/?term=vigetti+d&sort=date

Concepts (6)


LS1_11 - Biochemistry and molecular mechanisms of signal transduction - (2013)

LS1_11 - Biochemistry and molecular mechanisms of signal transduction - (2016)

LS1_2 - General biochemistry and metabolism - (2013)

LS1_2 - General biochemistry and metabolism - (2016)

LS1_7 - Carbohydrate synthesis, modification and turnover - (2013)

LS1_7 - Carbohydrate synthesis, modification and turnover - (2016)

Keywords (6)

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EXTRACELLULAR MATRIX
GLYCOBIOLOGY
HYALURONAN
LONG NON-CODING RNA
O-GLCNACYLATION
PROTEOGLYCANS
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Overview

Research Lines: Davide Vigetti His main lines of investigation include: Epigenetic and post-translational regulation: He studies how processes such as phosphorylation, acetylation, and O-GlcNAcylation regulate the synthesis of glycosaminoglycans. Tumor microenvironment: He analyzes the role of hyaluronic acid in cancer progression, angiogenesis, and chemoresistance mechanisms. Vascular and inflammatory diseases: He investigates how matrix accumulation influences the development of atherosclerosis, endothelial inflammation, and diabetes.
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Collaborates with (2)

Biochemistry of the extracellular matrix
Group
Centro di Ricerca per l'Invecchiamento di Successo
Group

Publications (237)

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Datasets

Awards and honors

Top cited FEBS Journal papers 2011, conferred by FEBS Journal - 2013
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Fellowship (2)

fs11 – Segretario/a - International society for hyaluronan sciences (ISHAS) (Stati Uniti) (2018 - 2021) 2018
fs11 – Segretario/a - Società Italiana per lo Studio del Connettivo (SISC) (Italia) (2017 - 2021) 2017
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Editorial Board (7)

Membro del Comitato Editoriale - MATRIX BIOLOGY - ISSN: 0945-053X - Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598 (2023 - ) 2023
Membro del Comitato Editoriale - PROTEOGLYCAN RESEARCH - ISSN: 2832-3556 - Hoboken New Jersey: Wiley Periodicals LLC, 2023- (2022 - ) 2022
Membro del Comitato Editoriale - BIOMOLECULES - ISSN: 2218-273X - Basel: MDPI (2021 - ) 2021
Membro del Comitato Editoriale - BMC CANCER - ISSN: 1471-2407 - London: BioMed Central, [2001]- Part of Springer Nature (2021 - ) 2021
Associate Editor di rivista o collana editoriale - FRONTIERS IN ONCOLOGY - ISSN: 2234-943X - Lausanne : Frontiers Editorial Office, 2011- (2020 - ) 2020
Membro del Comitato Editoriale - JOURNAL OF BIOLOGICAL CHEMISTRY - ISSN: 1083-351X - Bethesda, Md. : American Society for Biochemistry and Molecular Biology (2014 - 2025) 2014
Guest Editor di rivista o collana editoriale - BIOMED RESEARCH INTERNATIONAL - ISSN: 2314-6133 - [London]: [Hindawi] Cairo: Hindawi Publishing Corporation (2013 - 2013) 2013
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Research and teaching at institutions

Insegnamento di Biochimica per studenti del primo anno at: Accademia Italiana Medicina Osteopatica - Docente a contratto (01/10/2011 - 31/12/2018)20111001
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Congresses (7)

Altro ruolo - Hyaluronan 2023 the 14th International Conference on Hyaluronan , June 4-8, 2023, Portland (USA) (04/06/2023 - 08/06/2023) 20230604
Program chair (presidente/responsabile del comitato scientifico) - Hyaluronan 2019 The 12th International Conference on Hyaluronan) , June 9-13, 2019, Cardiff (UK) (01/01/2019 - 13/06/2019) 20190101
Program chair (presidente/responsabile del comitato scientifico) - Hyaluronan2017 The 11th International Conference on Hyaluronan) , June 11-15, 2017, Cleveland (USA) (01/01/2017 - 15/06/2017) 20170101
Program chair (presidente/responsabile del comitato scientifico) - 7-Lakes International Proteoglycans Conference - 10 – 14 September 2017 - Varese Italy (01/01/2017 - ) 20170101
Program chair (presidente/responsabile del comitato scientifico) - XXXVII Riunione Nazionale SISC (Società Italiana Studio del Connettivo), September 29-30, 2017, Como. (01/01/2017 - ) 20170101
Program chair (presidente/responsabile del comitato scientifico) - Hyaluronan 2015 The 10th International Conference on Hyaluronan) , June 2-7, 2013, Florence, Italy - Organizer. (01/01/2015 - ) 20150101
Program chair (presidente/responsabile del comitato scientifico) - Hyaluronan 2013 The 9th International Conference on Hyaluronan) , June 2-7, 2013, Oklahoma City - Chair of the Cardiovascular and Lymphatic Systems Section (01/01/2013 - ) 20130101
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Research Network (3)

CARES - Human ECM-based platform for anti-cancer drug testing - CARES (CAncer dRug tESting) (01/11/2023 - 31/10/2027)20231101
GLYCANC - Progetto di ricerca EU GLYCANC - Horizon2020 - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (01/07/2015 - 30/06/2019)20150701
INFLAMA - Matrix Macromolecules in inflammation (01/12/2011 - 30/11/2014)20111201
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Doctoral college (18)

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Università degli Studi INSUBRIA Varese-Como - SCIENZE DELLA VITA E BIOTECNOLOGIE-2024 (cycle: 40 - Year: 2024 2024 )
Università degli Studi INSUBRIA Varese-Como - SCIENZE DELLA VITA E BIOTECNOLOGIE-2023 (cycle: 39 - Year: 2023 2023 )
Università degli Studi INSUBRIA Varese-Como - SCIENZE DELLA VITA E BIOTECNOLOGIE-2022 (cycle: 38 - Year: 2022 2022 )
Università degli Studi INSUBRIA Varese-Como - SCIENZE DELLA VITA E BIOTECNOLOGIE-2021 (cycle: 37 - Year: 2021 2021 )
Università degli Studi INSUBRIA Varese-Como - SCIENZE DELLA VITA E BIOTECNOLOGIE-2020 (cycle: 36 - Year: 2020 2020 )
Università degli Studi INSUBRIA Varese-Como - SCIENZE DELLA VITA E BIOTECNOLOGIE-2019 (cycle: 35 - Year: 2019 2019 )
Università degli Studi INSUBRIA Varese-Como - SCIENZE DELLA VITA E BIOTECNOLOGIE-2018 (cycle: 34 - Year: 2018 2018 )
Università degli Studi INSUBRIA Varese-Como - SCIENZE DELLA VITA E BIOTECNOLOGIE-2017 (cycle: 33 - Year: 2017 2017 )
Università degli Studi INSUBRIA Varese-Como - BIOTECNOLOGIE, BIOSCIENZE E TECNOLOGIE CHIRURGICHE-2016 (cycle: 32 - Year: 2016 2016 )
Università degli Studi INSUBRIA Varese-Como - BIOTECNOLOGIE, BIOSCIENZE E TECNOLOGIE CHIRURGICHE-2015 (cycle: 31 - Year: 2015 2015 )
Università degli Studi INSUBRIA Varese-Como - BIOTECNOLOGIE, BIOSCIENZE E TECNOLOGIE CHIRURGICHE-2014 (cycle: 30 - Year: 2014 2014 )
Università degli Studi INSUBRIA Varese-Como - BIOTECNOLOGIE, BIOSCIENZE E TECNOLOGIE CHIRURGICHE-2013 (cycle: 29 - Year: 2013 2013 )
Università degli Studi INSUBRIA Varese-Como - BIOTECNOLOGIE-2012 (cycle: 28 - Year: 2012 2012 )
Università degli Studi INSUBRIA Varese-Como - BIOTECNOLOGIE-2011 (cycle: 27 - Year: 2011 2011 )
Università degli Studi INSUBRIA Varese-Como - BIOTECNOLOGIE-2010 (cycle: 26 - Year: 2010 2010 )
Università degli Studi INSUBRIA Varese-Como - BIOTECNOLOGIE-2009 (cycle: 25 - Year: 2009 2009 )
Università degli Studi INSUBRIA Varese-Como - BIOTECNOLOGIE-2008 (cycle: 24 - Year: 2008 2008 )
Università degli Studi INSUBRIA Varese-Como - BIOTECNOLOGIE-2007 (cycle: 23 - Year: 2007 2007 )
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Tutoring (4)

tutorship - Dottorandi/e - MACRÌ FEDERICA
tutorship - Assegnisti/e - D'ALOIA ALESSIA
tutorship - Dottorandi/e - PARNIGONI ARIANNA
tutorship - Dottorandi/e - CAON ILARIA
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Peer Reviewer (2)

2020-SC1-BHC-2018-2020: Proposal number: SEP-210530369 - commissioned by: European Commission - Research Executive Agency - 2021 2021
Progetto di ricerca MR/K010328 - commissioned by: MEDICAL RESEARCH COUNCIL CENTRE - 2019 2019
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Courses (9)

DMC0582 - CHEMISTRY AND BIOCHEMISTRY PROPAEDEUTICS

Primo Semestre (01/09/2025 - 15/11/2025) - 2025
6 CFU
75 hours

MED0021 - CHEMISTRY

Primo Semestre (06/10/2025 - 23/01/2026) - 2025
4 CFU
32 hours

MED0038 - BIOCHEMISTRY

Secondo Semestre (02/03/2026 - 05/06/2026) - 2025
6 CFU
60 hours

MED0199 - CHEMISTRY AND PREPARATORY BIOCHEMISTRY

Primo Trimestre (01/09/2025 - 15/11/2025) - 2025
6 CFU
75 hours

MED0523-2 - CLINICAL MOLECULAR BIOLOGY

Secondo Semestre (02/03/2026 - 05/06/2026) - 2025
2 CFU
24 hours

SME0197-1 - CHEMISTRY AND BIOCHEMISTRY -BA

Primo Semestre (06/10/2025 - 23/01/2026) - 2025
2 CFU
30 hours

SME0394 - CORE COMPETENCIES- BA

Primo Semestre (06/10/2025 - 23/01/2026) - 2025
5 CFU
75 hours

SME0574 - LABORATORY MEDICINE

Annuale (06/10/2025 - 05/06/2026) - 2025
7 CFU
84 hours

SME0669 - CHEMISTRY, BIOCHEMISTRY AND ELEMENTS OF LABORATORY MEDICINE

Primo Semestre (06/10/2025 - 23/01/2026) - 2025
10 CFU
80 hours
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