The main goal of the course is to provide students with an updated knowledge of the major classes of drugs in current clinical use and their respective mechanisms of action, at a molecular, cellular and systemic level. The course is fundamental to build the backbone of students’ pharmacological advanced cultural skills necessary for all the professional profiles working in the biomedical field On successful completion of the course, students will be able to: a) describe how drug modulation of the autonomic nervous system may impact the function of the major organ systems (cardiovascular system and kidney, respiratory and gastro-intestinal apparatuses) b) explain how drugs may control the activity of inflammatory and immune mediators c) describe the molecular mechanisms of drugs acting on the most prevalent diseases affecting the metabolism of sugars and lipids d) discuss the principles of antibacterial, antiviral and anticancer chemotherapy, and enlist the major classes of chemotherapeutic drugs
Prerequisiti
To fully understand the topics addressed in the present course, students must possess basic notions of cellular biology, human physiology and general and molecular pharmacology
Metodi didattici
The course consists of lectures that will be held with the aid of slide presentations
Verifica Apprendimento
A written test (essay-based) will be administered at the end of the course. It will be based on 3 open questions concerning different topics covered during the lessons and present in the program. A clear exposition of the topics, as well as the use of an adequate terminology are necessary to pass the exam. Students must score at least 18/30 in order to pass the test
Contenuti
Drugs acting on the peripheral and autonomous nervous systems Local anaesthetics Cardiac rhythm and antiarrhythmics Cardiac contractility and inotropic agents Cardiac oxygen demand and supply and antischemic drugs Pharmacology of hemostasis and thrombosis Hypertension and its treatment Atherosclerosis and dyslipidemias and their treatment Diabetes and its treatment Pharmacology of inflammation and immunity Chemotherapy of Infectious Diseases Cancer Chemotherapy
Lingua Insegnamento
ITALIANO
Altre informazioni
Contact information: tiziana.rubino@uninsubria.it The teacher receives students by appointment requested by email or before/after class (while teaching module is ongoing)