ALBERIO TIZIANA

Curriculum Vitae – Tiziana Alberio

Associate Professor of Biochemistry at the University of Insubria, Via Ravasi 2, 21100 Varese, Italy.

Tiziana Alberio was born in Busto Arsizio (VA), Italy, on May 3, 1981.

Her research mainly focuses on the pathogenetic mechanisms underlying neurodegeneration. In particular, her work has centered on Parkinson’s disease and, in recent years, on amyotrophic lateral sclerosis, Alzheimer’s disease, Spinocerebellar Ataxia (SCAR30). She is currently working on a drug repurposing project for fibromyalgia.
She has adopted a multidisciplinary approach (combining biochemistry, proteomics, and systems biology) to investigate: (i) the role of mitochondrial dysfunction in neurodegeneration; (ii) specific and shared pathways of neurodegeneration; and (iii) protein network construction to better understand the molecular mechanisms underlying neurodegenerative diseases.

She served as Executive Manager of the Italian initiative “Standardization of mitochondrial proteome analysis” within the mitochondrial Human Proteome Project (mt-HPP), part of the Human Proteome Project promoted by the Human Proteome Organization (HUPO). She was an elected member of the Executive Board of the Italian Proteomics Association (ItPA) for two terms (2019–2021, Board Member; 2022–2024, Treasurer) and is currently a member of the Education Committee of the European Proteomics Association (EuPA). She is also a faculty member of the PhD School in “Experimental and Translational Medicine”.

Tiziana Alberio is the author of 53 full papers published in international peer-reviewed journals (h-index = 21; 1,237 total citations according to Scopus). For further details, see her Scopus profile: https://www.scopus.com/authid/detail.uri?authorId=24398308700
She obtained the National Scientific Qualification (ASN) for Full Professor in BIOS/07 (formerly BIO/10) Biochemistry in 2021.

Education and Training
- April 2017 – National Scientific Qualification for Associate Professor (ASN 2016) in Biochemistry (05/E1), Molecular Biology (05/E2), and Applied Biology (05/F1).
- December 2, 2010 – PhD in Neurobiology, University of Insubria. Thesis: “The proteomic approach to investigate Parkinson’s disease: pathogenetic mechanisms and biomarker discovery.”
- December 13, 2006 – M.Sc. in Applied Biology for Biomedical Research, University of Insubria. Thesis: “Evaluation of the effects of the DeltaNp73beta isoform overexpressed in an in vitro model of non-small cell lung carcinoma.” Final grade: 110/110 cum laude (with honors).
- November 18, 2004 – B.Sc. in Biology, University of Insubria. Thesis: “Expression analysis of APOBEC3G and APOBEC3F: genes potentially protective against HIV infection.” Final grade: 110/110 cum laude (with honors).
- July 2000 – Scientific high school diploma, “Daniele Crespi” Linguistic High School, Busto Arsizio (Italy). Final grade: 100/100.

Research and Professional Experience
- 2019–2024 – Elected member of the Executive Board of the Italian Proteomics Association (ItPA).
- Since 2021 – Member of the Education Committee of the European Proteomics Association (EuPA).
- Since 2021 – Associate Professor of Biochemistry, University of Insubria. Coordinator of research projects on neurodegenerative mechanisms and biomarker validation in Parkinson’s disease. Teaching in the M.Sc. in Biomedical Sciences and M.Sc. in Environmental Sciences, and in the PhD program in Experimental and Translational Medicine. Supervisor of post-docs, PhD students, and undergraduate and graduate students.
- June 2018 – 2021 – Tenure-track Researcher in Biochemistry (RUTD-B), University of Insubria. Coordination of research projects on neurodegenerative mechanisms and biomarker validation in Parkinson’s disease. Teaching in the M.Sc. in Biomedical Sciences, PhD School in Experimental and Translational Medicine, and Master’s program in Chemical Risk Assessment and Management.
- May 2013 – May 2018 – Assistant Professor in Biochemistry (RUTD-A), University of Insubria. Co-PI of research projects on neurodegenerative mechanisms. Teaching in the M.Sc. in Biomedical Sciences, PhD School, and Master’s program in Chemical Risk Assessment and Management.
- April 2011 – May 2013 – Postdoctoral Research Fellow (Lombardy Region grant). Mitochondrial proteomics and biomarker discovery in Parkinson’s disease, University of Insubria. Research project in collaboration with Waters Corp.
- January 2011 – April 2011 – Research Fellow. Initiated the project “Parkinson Informative System, ParIS” in collaboration with Biodigitalvalley s.r.l., funded by the Autonomous Region of Valle d’Aosta.
- October 2007 – October 2010 – PhD student in Neurobiology. Activities included cell culture optimization, two-dimensional electrophoresis, image analysis, bioinformatics, lymphocyte isolation from human blood, supervision of student reports, and contribution to grant applications.
- April 2007 – September 2007 – Recipient of the Ingenio Research fellowship, Lombardy Region initiative.

Awards and Invited Talks
- 2025 – Selected presentation at the joint meeting of the “Proteins” and “Nucleic Acids” divisions of the Italian Society of Biochemistry (SIB): “Exploring the role of RAB9 and alternative mitophagy in Parkinson's Disease”, University of Brescia, May 29–30, 2025.
- 2023 – Invited speaker at the 32nd Human Brain Proteome Project Workshop: “Addressing microglial dysfunction in Alzheimer's disease: a role for endocannabinoid signaling in immunosenescence”, São Sebastião, Brazil, May 21–23, 2023.
- 2019 – Invited talk: “Exploring the mitochondrial degradome by the TAILS proteomics approach in a cellular model of Parkinson’s disease”, VI International Caparica Conference on Analytical Proteomics, Lisbon, July 8–11, 2019.
- 2018 – Selected participation in the Zambon Open Accelerator Program with the project “ParkinTest”, a diagnostic test for Parkinson’s disease.
- 2016 – Invited speaker at the IX Italian Proteomics Association Congress (ItPA), Perugia: “Update on the standardization initiative” and “Cellular models of Parkinson's disease: a combined omics and targeted approach to unravel pathogenetic markers.”

Editorial and Reviewing Activities
- Peer reviewer for numerous international journals, including: Annals of Biochemistry, Biochimica et Biophysica Acta, Biomarkers in Medicine, Biomedicine & Pharmacotherapy, BMC Medical Genomics, Chemical Neuroscience, Chemical Research in Toxicology, EuPA Open Proteomics, Frontiers in Cell and Developmental Biology, Frontiers in Genetics, Frontiers in Pharmacology, Genetics, International Journal of Molecular Sciences, Immunotoxicology and Immunopharmacology, Journal of Proteome Research, Journal of Proteomics, Molecular Neurobiology, Neurochemistry International, Neuroscience, npj Parkinson's Disease, Proteome Science, Science Advances, Scientific Reports.
- Associate Editor of BMC Genomics, Proteomics section.

Research Funding (Recent Years)
- 2017 – One-year post-doc grant, University of Insubria. Role: Supervisor.
- 2019 – One-year post-doc grant, University of Insubria. Role: Supervisor.
- 2020–2023 – PRIN2017 National Strategic Research Project: “Addressing microglial dysfunction in Alzheimer's disease: a role for endocannabinoid signaling in immunosenescence”. Ministry of University and Research. Role: Unit PI.
- 2024–ongoing – PRIN 2022 PNRR Project P2022LTSE9 YOMP: “Yeast model and omics studies to deepen knowledge about the mitochondrial metallopeptidase PITRM1 in health and disease”. Ministry of University and Research. Role: Unit PI.
- 2024–ongoing – European Union – Next Generation EU, PNRR, Mission 4, Component 2, Investment 4.1, Ministerial Decree no. 118/2023. Joint PhD supervision for a double-degree program: “A new artificial intelligence drug repurposing approach for fibromyalgia” between the University of Insubria and Universidad Católica de Valencia, Spain.