The Center for Neuroscience Research of the University of Insubria was founded in 2003 with the aim of promoting research in fields related to the Neurosciences, in particular the study of functional and neurodegenerative pathologies of the nervous system, with cell and molecular biology, biochemistry and physiology, neuropharmacology, neuroimmunology and systems biology approaches.
The Center aims at offering a meeting point for research groups in the biomedical and clinical area in our University, favoring knowledge exchange and multidisciplinary collaborations.
The training and education of young researchers working in the member laboratories is crucially important to the Center, and to this aim periodic meetings of the member labs are organized, where young collaborators are invited to present and discuss their research activities.
Moreover, the Center organizes scientific workshops as well as public seminars on neuroscientific topics, centered on physiological and pathological mechanisms of central nervous system operation, and on new avenues to therapeutic interventions in neurological and psychiatric disorders.
Address:
Via Manara 7, 21052 Busto Arsizio (VA)
date/time interval:
(March 3, 2003 - )
Overview
Acronym
CNS
Term type
Gruppo di ricerca strategica
Linked Units
Research Fields
Concepts (22)
Overview (10)
Biochemistry and Functional Proteomics Laboratory: pathogenetic mechanisms and peripheral biomarkers discovery for Parkinson disease (Alberio, Fasano)
Cellular Neurophysiology Laboratory: functional effects of acute stress on synaptic transmission and membrane excitability in the rodent prefrontal cortex (Forti)
Cellular and Molecular Physiology Laboratory: structure, function and regulation of ion channels and membrane transporters involved in several diseases, including Parkinson and chronic pain, through the use of electrophysiological, immunochemical, biochemical, fluorometric and molecular biology techniques (Bossi, Roseti)
Center for Research on Medical Pharmacology: neuroendocrine modulation of the immune system, pharmacological modulation of endogenous cathecolamines in human lymphocytes and its functional physiological and pathological relevance in Parkinson disease and multiple sclerosis (Cosentino, Marino)
Laboratory “The Protein Factory 2.0”. Molecular mechanisms involved in regulation of catabolism of the atypical neuromodulator D-serine e D-aspartate in the brain (Sacchi, Pollegioni)
Molecular Neurobiology Laboratory: characterization of the functions of the CDKL5 protein kinase in the nervous system and the consequences of its ablation, leading to severe human neurological disorder (Kilstrup-Nielsen)
Neurology Group. Neurodegenerative disorders (dementia, movement-related disorders, ALS); imaging biomarkers in mild cognitive decay; role of neuroinflammation and peripheral immunity in Parkinson and Alzheimer disease; peripheral biomarkers in neurodegenerative processes: d-serine. Encepalopathies secondary to infectious diseases (SARS COV-2), dysimmune encepalopathies (rapidly progressing dementia) (Mauri)
Neuropsychopharmacology Group. Evaluation of 1) the therapeutic potential of phytocannabinoids in autism spectrum disorder models; 2) the role of the endocannabinoid system in the pathogenesys of psychiatric disorders; 3) the ability of cannabidiol to modulate adverse long-term effects induced by brain exposure to delta-9-tetrahydrocannabinol in adolescence; 4) role of the endocannabinoid system on brain maturation processes occurring in adolescence (Rubino, Zamberletti)
Physiology and pharmacology of the enteric nervous system: cellular and molecular mechanisms of the adaptation of the enteric nervous system. Physiopathology of the digestive system. Role of the interaction between the enteric microenvironment and commensal microbiota in the development of enteric neuropathies linked to irritable bowel syndrome and to the inflammatory bowel disease (Giaroni)
Research Group on Psychiatry. Study of resilience: pharmacogenetics clinical applications (treatment of mood diseases). Dissociative consciousness diseases; correlation between genetic and inflammatory biomarkers and mood diseases. Ethnopsychiatry and cultural psychiatry; migration trauma-linked psychopathology; post-traumatic stress disorder; mental pain and suicide risk prevention (Callegari)
No Results Found
Affiliation
Collaboration with other Workgroups (2)
Members (23)
Outputs
Publications (43)
Contact
Email address
centro.neuroscienze@uninsubria.it